Endocrinologist

Spoke with the endocrinologist today. He showed me some insulin graphs. Apparently even on Lantus, individuals who don't produce insulin will have higher peaks and valleys. Isaac has been fairly stable, leading the endocrinologist to believe that Isaac is able to produce more insulin now. He does well for about 18 hours on one dose of Lantus and then the endo theorizes that his pancreas cells give out and the Lantus also peters out. It trends upwards fairly sharply after that point. I asked about doing another C-peptide test, and he said that was something we could definitely do down the road. It would show whether his insulin levels have increased, but he was sure just by looking at his glucose levels that he was producing more.

Great news! Perhaps, perhaps, this is transient diabetes. Still not possible to tell, but maybe! At any rate he only needs a small dose of Lantus, so that in and of itself is great.

For the Inordinately Curious

Some articles I've dug up on NDM...

Some were more interesting/useful than others.

From the journal Diabetes (2005)
and another Diabetes (2003)
Diabetes Care (2004)
Journal of Medical Genetics (2002)
Brief overview Athena Diagnostics
Orhpanet Journal of Rare Diseases (2007)
New England Journal of Medicine (2004)
This next one you'll have to download the pdf...

Journal of Clinical Endocrinology & Metabolism (2004)

There are some others I found interesting, but I signed personal use agreements, so can't post them. One from Endocrine Reviews published in 2008 was particularly good...

Wish I had access to a university library, then I could pull all kinds of articles.